Protein acetylation affects acetate metabolism, motility and acid stress response in E. coli
Tobias Fuhrer and Uwe Sauer lab contributed to the study lead by Manuel Cánovas (Uni. de Murcia, Spain).
by
Nicola Zamboni
An integrated analysis of proteomic, transcriptomic and metabolic flux data reveals functional roles of protein acetylation in E. coli. Acetylation regulates protein function directly, by modulating metabolic enzyme activity, or indirectly by affecting transcriptional regulators.
Reference
Castaño‐Cerezo S, Bernal V, Post H, Fuhrer T, Cappadona S, Sánchez‐Díaz NC, Sauer U, Heck A, Altelaar AVM, Cánovas M, Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli, Molecular Systems Biology (2014)10:762. external pageDOI10.15252/msb.20145227call_made