Donation of Lotte and Adolf Hotz-Sprenger Foundation for Prostate Cancer Digital Biobanking
With its generous donation to the ETH Zurich Foundation Lotte and Adolf Hotz-Sprenger Foundation supports the project "Prostate Cancer Digital biobanking" within the "Personalized Medicine" initiative of ETH Zurich, the University Hospital Zurich and the University of Zurich.
Ulrich Genick awarded with “Golden Owl” of the VSETH
for outstanding contributions to teaching. Congratulations!
Pseudo-transition Analysis Identifies the Key Regulators of Dynamic Metabolic Adaptations from Steady-State Data
The Sauer Lab developed an experimental-computational approach to identify regulatory needles in metabolic haystacks. By using steady-state 13
C flux, metabolites and transcript data, the approach revealed the sparse and transition-dependent regulators that drive transitions between carbon sources in Escherichia coli
. Thus, pseudo-transition analysis is a novel approach to efficiently explore the vast regulatory landscape of dynamic adaptations using relatively few stationary observations.
Real-time metabolome profiling of the metabolic switch between starvation and growth
The Zamboni and Sauer Lab developed a platform for real-time metabolome profiling by directly injecting living bacteria, yeast or higher cell suspensions into a high-resolution time-of-flight mass spectrometer. We congratulate Hannes and all the coauthors.