Duncan Holbrook-Smith won a prestigious HFSP scholarship for his postdoc project at the Sauer lab, on exploiting non-targeted metabolomics for parallelized discovery of chemical probes for receptor-like proteins, and using those chemical probes to better understand the specific roles of receptor-like proteins in that system. Now he has the problem of deciding which fellowship to accept………
Michael Zimmermann and Paul Murima won the Swiss TB 2017 Award!
Michael Zimmermann and Paul Murima won the Swiss TB 2017 Award for their Nature Communications paper "A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria." CONGRATULATIONS!
Genome-wide landscape of gene-metabolite interactions charted for bacterium
How do gene (knock-outs) affect metabolite levels? We tested this systematically for > 3'800 genes in E. coli
and found several suprises.
Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli
About 15'000 high-throughput, non-targeted metabolomics analyses were acquired to study >1'200 functionally uncharacterized proteins. The study was just published by Daniel Sévin and co. in Nature Methods.