Szymon Jozefczuk

I am a molecular biologist with a strong interest in metabolism related regulatory relations between small molecules and genes. I did my PhD in Max Planck Institute of Molecular Plant Physiology in Potsdam where I investigated stress responses of bacteria Escherichia coli based on the analysis of combined global transcript and metabolic readouts.

The primary project on which I work in Sauer group is a regulation of nitrogen metabolism in yeast Saccharomyces cerevisiae. Here I am especially interested in uncovering a potential metabolic signal linking changes in nitrogen availability and quality, TOR kinase activity, and downstream events of cellular response.

Publications

Systems biology

Jozefczuk S, Klie S, Catchpole G, Szymanski J, Cuadros-Inostroza A, Steinhauser D, Selbig J, Willmitzer L. Metabolomic and transcriptomic stress response of Escherichia coli. Mol Syst Biol. 2010; 6: 364.

Szymanski J, Jozefczuk S, Nikoloski Z, Selbig J, Nikiforova V, Catchpole G, Willmitzer L. Stability of Metabolic Correlations under Changing Environmental Conditions in Escherichia coli – A Systems Approach. PLoS One. 2009; 4(10): e7441.

Plant science

Skirycz A, Jozefczuk S, Stobiecki M, Muth M, Zanor MI, Witt I, Mueller-Roeber B. Transcription factor AtDOF4;2 affects phenylpropanoid metabolism in Arabidopsis thaliana. New Phytologist, 2007;175(3):425-38.