Dr. Christopher Barnes

ETH Zürich Dr. Christopher Barnes Institut f. Molekulare Systembiologie HPT E 51 Wolfgang-Pauli-Str. 16 8093 Zürich Phone: +41 44 633 34 03 E-Mail:

Chris did his PhD in the Department of Chemical Engineering at the University of Washington in Seattle. His thesis mainly involved the characterization of biomaterials derived from decellularized pig tissues using a surface –sensitive mass spectrometry technique called time-of-flight secondary ion mass spectrometry (ToF-SIMS). Chris came to IMSB to learn how to apply proteomics and other systems biology concepts to the design and creation of new more effective bioengineering solutions for healthcare. He is currently working on two projects. The first is a study designed to identify novel phosphorylation substrates using an in vitro kinase phosphorylation assay combined with a phosphoenrichment purification and final identification of phosphosites with high-resolution mass spectrometry. The second project is a collaboration with the laboratory of Professor Jeffrey Hubbell at Ecole Polytechnique Fédérale de Lausanne where breast cancer tumor cells are encapsulated in polyethylene glycol hydrogels and studied with targeted proteomics for the purpose of creating a more biologically accurate synthetic tissue engineered model of metastasis.

Chris is a fellow of The Whitaker Foundation which is a private funding source for biomedical engineering research and education in the United States.