Publications

Main content

Full list on Pubmed
Full list on Google Scholar
Full list on ResearchGate

 

Accordion. Press Tab to navigate to entries, then Enter to open or collapse content.

 

Recent publications

  • Fuhrer T et al, Genomewide landscape of gene–metabolome associations in Escherichia coli, Molecular Systems Biology, 2017, 13:907 doi journal
  • Zampieri M et al, Frontiers of high-throughput metabolomicsCurr Opin Chem Biology. 2017, 36:15 doi
  • Dubuis S et al, Metabotypes of breast cancer cell lines revealed by non-targeted metabolomics, Metabolic Engineering, doi
  • Sévin et al, Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli, Nature Methods, 2016, doi
  • Geiger et al, L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity, Cell, 2016, doi
    Highlighted in Cell Metabolism by NP Restifo et al doi
  • Kogadeeva M, Zamboni N, SUMOFLUX: A Generalized Method for Targeted 13C Metabolic Flux Ratio Analysis, PLOS Computational Biology, 2016, doi
  • Williams et al, Systems proteomics of liver mitochondria function, Science, 2016, 352, doi
  • Ewald J, Kühne A, Zamboni N, Skotheim J, The Yeast Cyclin-Dependent Kinase Routes Carbon Fluxes to Fuel Cell Cycle Progression, Molecular Cell, 2016, 61, 532–545 Pubmed doi
  • Vanderperre B et al. Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet, PLOS Genetics, 2016; 12(5):e1006056. Pubmed doi

Applications: human and animal models

  • Dubuis S, Metabotypes of breast cancer cell lines revealed by non-targeted metabolomics, Metabolic Engineering, 2017, doi
  • Geiger et al, L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor ActivityCell, 2016, doi
  • Williams et al, Systems proteomics of liver mitochondria functionScience, 2016, 352, doi
  • Kuehne A, Emmert H, et al. Acute activation of oxidative pentose phosphate pathway as first-line response to oxidative  stress in human skin cells, Molecular Cell, 2015, 59(3): 359–371, Pubmed Journal link doi 
    Editor's choice in Science Signaling link
    Commentary in Molecular Cell by Dick and Ralser link
  • Mirtschink P et al, HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease, Nature, 2015, Pubmed doi
    Featured in ETH Life link
  • Wu Y et al, Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population, Cell, 2014; 158(6):1415-1430 Pubmed doi
  • Weimer S et al, D-Glucosamine supplementation extends life span of nematodes and of ageing mice, Nat Commun. 2014 Apr 8;5:3563 Pubmed doi
    Featured in ETH Life link
  • Knobloch M et al, Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis, Nature, 2013; 493, 226–230 Pubmed doi
  • Herzig S et al, Identification and functional expression of the mitochondrial pyruvate carrier, Science, 2012; 337(6090):93-6 Pubmed doi
    Commentary in Cell Metabolism by AP Halestrap link
    Highlight in Science by AS Divakaruni and AN Murphy link
  • Yuneva M et al, Deficiency in glutamine but not glucose selectively induces apoptosis in human cells with abnormal activity of MYC, J Cell Biol, 2007; 178(1):93-105 Pubmed

Applications: Microorganisms

  • Fuhrer T, Zampieri M, Sévin DC, et al, Genomewide landscape of gene–metabolome associations in Escherichia coliMolecular Systems Biology, 2017, 13:907 doi journal
  • Sévin et al, Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli, Nature Methods, 2016, doi
  • Ewald J, Kühne A, Zamboni N, Skotheim J, The Yeast Cyclin-Dependent Kinase Routes Carbon Fluxes to Fuel Cell Cycle Progression, Molecular Cell, 2016, 61, 532–545 doi
  • Link H, Fuhrer T, et al. Real-time metabolome profiling of the metabolic switch between starvation and growthNature Methods, 2015, Journal link doi 
    Featured in ETH Life link
    Highlighted in Nature Chemical Biology link
  • Zimmermann M, Kuehne A, et al, Dynamic exometabolome analysis reveals active metabolic pathways in non‐replicating mycobacteriaEnvironmental Microbiology, 2015, doi
  • Ewald JC et al. The integrated response of primary metabolites to gene deletions and the environment, Molecular Biosystems, 2013 Pubmed doi
  • Zampar GG et al. Temporal system-level organization of the switch from glycolytic to gluconeogenic operation in yeast, Molecular Systems Biology, 2013; 9:651 Pubmed doi
  • Schuetz R et al. Multidimensional optimality of microbial metabolism, Science, 2012; 336: 601-4 Pubmed doi
    Featured in Science by E. Noor and R. Milo link
  • Fendt SM et al, Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity, Molecular Systems Biology. 2010;6:356 Pubmed

Metabolomics

  • Sévin et al, Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli, Nature Methods, 2016, doi
  • Link H, Fuhrer T, et al. Real-time metabolome profiling of the metabolic switch between starvation and growthNature Methods, 2015, doi
    Featured in ETH Life link
    Highlighted in Nature Chemical Biology link
  • Fuhrer T et al, High-throughput, accurate mass metabolome profiling of cellular extracts by flow injection - time-of-flight mass spectrometry, Analytical Chemistry, 2011;83(18):7074-80 Pubmed
  • Büscher J, Moço S, Sauer U, Zamboni N, Ultra-high performance liquid chromatography-tandem mass spectrometry method for fast and robust quantification of anionic and aromatic metabolites. Analytical Chemistry 2010; 82(11):4403-4412 Pubmed
  • Ewald JC, Heux S, Zamboni N, High-throughput quantitative metabolomics: a workflow for cultivation, quenching and analysis of yeast in a multi-well format. Analytical Chemistry 2009; 81(9):3623-3629 Pubmed
  • Büscher JM, Czernik D, Ewald JC, Sauer U, Zamboni N, Cross-Platform Comparison of Methods for Quantitative Metabolomics of Primary Metabolism, Analytical Chemistry 2009; 81(6):2135-2143 Pubmed
  • Zimmermann M, Sauer U, Zamboni N, Quantification and Mass Isotopomer Profiling of α-Keto Acids in Central Carbon Metabolism. Analytical Chemistry, 2014; 86(6):3232-7 Pubmed
  • Zimmermann M, Thormann V, Sauer U, Zamboni N, Non-targeted profiling of coenzyme A thioesters in biological samples by tandem mass spectrometry. Analytical Chemistry, 2013; 85 (17): 8284–8290 Pubmed

Metabolic Flux Analysis

  • Kogadeeva M, Zamboni N, SUMOFLUX: A Generalized Method for Targeted 13C Metabolic Flux Ratio Analysis, PLOS Computational Biology, 2016, doi
  • Hörl M, Schnidder J, Sauer U, Zamboni N, Non-stationary 13C-metabolic flux ratio analysis, Biotechnology & Bioengineering, 2013, 110(12):3164-76. Pubmed doi
  • Rühl M, Rupp B, Nöh K, Wiechert W, Sauer U, Zamboni N, Collisional fragmentation of central carbon metabolites in LC-MS/MS increases precision of 13C metabolic flux analysis. Biotechnology & Bioengineering. 2012 Mar;109(3):763-71 Pubmed
  • Zamboni N et al, 13C-based metabolic flux analysis, Nature Protocols 2009; 4(6):878-892 Pubmed doi
  • Zamboni N, Fischer E, Sauer U, FiatFlux-a software for metabolic flux analysis from 13C-glucose experiments, BMC Bioinformatics. 2005;6:209 Pubmed
  • Fischer E, Zamboni N, Sauer U, High-throughput metabolic flux analysis based on gas chromatography-mass spectrometry derived 13C constraints, Analytical Biochemistry, 2004; 325(2):308-16 Pubmed

Reviews

  • Zampieri M, Sekar K, Zamboni N, Sauer U, Frontiers of high-throughput metabolomics, Curr Opin Chem Biology. 2017, 36: 15 doi
  • Zamboni N, Saghatelian A, Patti GJ, Defining the Metabolome: Size, Flux, and RegulationMolecular Cell. 2015, 58: 699–706, doi
  • Fuhrer T, Zamboni N. High-throughput discovery metabolomics, Curr Opin Biotechnol. 2015:31:73-78 Pubmeddoi
  • Sévin DC, Kuehne A, Zamboni N, Sauer U. Biological insights through nontargeted metabolomics, Curr Opin Biotechnol. 2015:34 doi
  • Zamboni N. 13C metabolic flux analysis in complex systems, Curr Opin Biotechnol. 2011;22:103-108 Pubmed doi
  • Zamboni N, Sauer U, Novel biological insights through metabolomics and 13C-flux analysis, Curr Opin Microbiol 2009;12:553-8 Pubmed doi
  • Sauer U, Heinemann M, Zamboni N, Getting close to the whole picture, Science 2007; 316:550-551 Pubmed
 
 
Page URL: http://www.imsb.ethz.ch/research/zamboni/publications.html
19.02.2017
© 2017 Eidgenössische Technische Hochschule Zürich