Metabolic Changes During Skin Ageing and Skin Differentiation
Metabolic processes are heavily involved in cellular ageing and cell differentiation. My project aims to apply a systems biology approach to investigate the impact of metabolic changes on different cellular processes of the human skin. For this purpose I use various cellular differentiation and ageing models together with mass spectrometry methods to analyze the metabolome at different cellular stages. In combination with gene expression assays this analysis should lead to a deeper understanding of the influences of metabolic changes on the human skin.