Dr. Ryohei Yagi

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Ryohei Yagi

Dr. Ryohei Yagi

ETH Zurich

Inst. f. Molekulare Systembiologie

Dr. Ryohei Yagi

HPT C 61

Auguste-Piccard-Hof 1

8093 Zürich

Switzerland

Ryohei received his Bachelor's and Master's degrees in Engineering from Kyoto Institute of Technology, Japan. He received his Ph.D. on Molecular Medicine from Kyoto University, Japan. The focus of the Ph.D. thesis was to investigate the mechanisms regulating the oncogenic transcription factor Runx. In the course of this research, he found Yap as a transcriptional co-activator. He then worked at the Osaka Bioscience Institute, Japan. During this period, his work focused on understanding the molecular mechanisms underlying cell migration in cultured mammalian cells and integrin-mediated cell adhesions in Drosophila. He then joined Konrad Basler's group at University of Zurich, Switzerland. There he developed various in vivo genetic tools and the techniques to study cell signaling in Drosophila. He joined the Hafen group in 2015 and works on a systems approach to study size control in Drosophila.

Publications


Gerald Schwank, Sascha Dalessi, Schu-Fee Yang, Ryohei Yagi, Aitana Morton de Lachapelle, Markus Affolter, Sven Bergmann, and Konrad Basler
Formation of the long range dpp morphogen gradient.
PLoS Biol. 9:e1001111. 2011

Gerald Schwank, Gerardo Tauriello, Ryohei Yagi, Elizabeth Kranz, Petros Koumoutsakos, and Konrad Basler, Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation.
Dev Cell. 20:123-30. 2011

Ryohei Yagi, Franz Mayer, and Konrad Basler
Refined LexA transactivators and their use in combination with the Drosophila Gal4 system.
Proc Natl Acad Sci U S A. 107:16166-71. 2010

Shigeru Hashimoto, Ari Hashimoto, Atsuko Yamada, Hiroko Yamamoto, Chie Kojima, Tomonari Tsutsumi, Mikito Higashi, Akira Mizoguchi, Ryohei Yagi, and Hisataka Sabe
A novel mode of action of an ArfGAP, AMAP2/PAG3/Pap α, in Arf6 function
J. Biol. Chem. 279: 37677-37684. 2004

Asako Tsubouchi, Junko Sakakura, Ryohei Yagi, Yuichi Mazaki, Erik Schaefer, Hajime Yano and Hisataka Sabe.
Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration.
J. Cell Biol. 159: 673-683. 2002.

Ryohei Yagi, Satoshi Ishimaru, Hajime Yano, Ulrike Gaul, Hidesaburo Hanafusa and Hisataka Sabe.
A novel muscle LIM-only protein is generated from paxillin gene locus in Drosophila.
EMBO R., 2:814-820. 2001.

Yuichi Mazaki, Shigeru Hashimoto, Katsuya Okawa, Asako Tsubouchi, Kuniaki Nakamura, Ryohei Yagi, Hajime Yano, Akiko Kondo, Akihiro Iwamatsu, Akira Mizoguchi and Hisataka Sabe.
PAG1/KIAA0148, an ARFGAP protein, helps to regulate focal adhesion recruitment of paxillin and actin stress fiber formation.
Mol. Biol. Cell., 12:645-662. 2001.

Fumihiko Kanai, Paola A. Marignani, Dilara Sarbassova, Ryohei Yagi, Randy A. Hall, Mark Donowitz, Akihiko Hisaminato, Tsutomu Fujiwara, Yoshiaki Ito, Lewis C. Cantley and Michael B. Yaffe.
TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ-domain proteins.
EMBO J., 19:6778-6791. 2000.

Ryohei Yagi, Lin-Feng Chen, Katsuya Shigesada, Yota Murakami and Yoshiaki Ito.
A WW domain-containing Yes-associated protein (YAP) is a novel transcriptional co-activator.
EMBO J., 18:2551-2562. 1999.

 
 
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