Prof. Dr. Manfred Claassen
Manfred Claassen joined the Institute of Molecular Systems Biology at the ETH Zurich as an Assistant Professor for computational biology in January 2013.
He has carried out parallel studies in Biochemistry and Computer Science at the University of Tübingen and been awarded a Diploma in Biochemistry in 2004 and a Diploma in Computer Science in 2006. In 2010 he obtained a PhD from ETH Zurich. During his doctoral studies he developed statistical methods to design and validate proteome measurements. In 2011 he moved on for postdoctoral training with Daphne Koller at Stanford University, where he focused on inferring informative network models from single cell resolved perturbation studies.
His research aims at elucidating the composition of heterogeneous cell populations and how these implement function in the context of cancer and immune biology by jointly evaluating single cell and genome wide measurements. The Claassen group builds on concepts from statistics, machine learning and mathematical optimization to develop probabilistic approaches to describe biological systems, learn these descriptions from data and to design experiments to validate hypotheses following from computational analyses.