Dr. Marija Buljan
Marija graduated Molecular Biology at the Faculty of Science in Zagreb, Croatia, where she also did her diploma thesis in Prof Kristian Vlahovicek's Bioinfomatics group. In 2006, she joined the Wellcome Trust Sanger Institute's PhD program in Computational genomics. Her PhD thesis 'Mechanisms of change in protein architecture' was done in the Pfam group, under the supervision of Dr Alex Bateman. As a part of the Wellcome Trust PhD programme she also did rotation projects in the groups of Dr Anton Enright, Prof Manolis Dermitzakis and Dr Julian Parkhill.
In 2010, Marija was awarded with a PhD from the University of Cambridge. Her following step was a postdoctoral research in Dr Madan Babu's Systems Biology group at the MRC Laboratory of Molecular Biology in Cambridge. In 2013, she joined the Signaling and Functional Genomics division at the German Cancer Research Center in Heidelberg led by Prof Michael Boutros. Marija has started her work in Prof Ruedi Aebersold's group in 2015 and in her research she will focus on how disease-associated mutations affect the choice and affinity of protein interactions and how this then affects the cellular function.
- SystemsX fellowship 2013
- CellNetworks fellowship 2013
- Wellcome Trust PhD Fellowship 2006
- Outstanding student award, Faculty of Science, University of Zagreb 2005
Publications (* denotes a corresponding author)
- van der Lee R, Buljan M, et. al. Classification of intrinsically disordered regions and proteins. Chem Rev 2014
- Mitrea DM, Grace CR, Buljan M, et. al. Structural polymorphism in the N-terminal oligomerization domain of NPM1. PNAS 2014
- White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, et. al. Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell 2013
- Buljan M*, et. al Alternative splicing of intrinsically disordered regions and rewiring of protein interactions. COSB 2013
- Buljan M*, et. al Tissue-specific splicing of disordered segments that embed binding motifs rewires protein interaction networks. Mol Cell 2012
- Buljan M*, et. al Quantifying the mechanisms of domain gain in animal proteins. Genome Biol 2010
- Buljan M, et. al The evolution of protein domain families. Biochem Soc Trans 2009