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Metabotypes of breast cancer cell lines revealed by non-targeted metabolomics
A metabolome and network centric analysis of 18 breast cancer cell lines reveals a fine-grained metabolic heterogeneity. The study will appear in a special issue of Metabolic Engineering devoted to cancer metabolism. We thank the team of our collaborator Prof. Almut Schulze (Würzburg).
Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli
About 15'000 high-throughput, non-targeted metabolomics analyses were acquired to study >1'200 functionally uncharacterized proteins. The study was just published by Daniel Sévin and co. in Nature Methods.
Sauer group: Interplay of posttranslational modification sites in enzyme activity regulation (Master project)
Research project available on investigating the interplay and protein activity fine-tuning of different posttranslational modifications (PTM) sites
Visit of Emily LeProust at ETH
The Christen lab is proud to host Emily LeProust, CEO of Twist Biosciences during her visit at ETH.
Sauer group: Metabolomics and Flux Balance Analysis in Saccharomyces cerevisiae (Semester/Master Project)
Research project available on investigating the regulation of metabolism in S. cerevisiae, via enzyme phosphorylation
Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals
Histone modification profiling in rare stem cell populations: our collaborative work on the epigenetics in muscle stem cell aging got published in Nature!